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related danger to obtaining organisms and environments.113 QSAR models are typically determined by the

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* Status: “Initiated”: Chemicals which were designated for a substantial precedence or for which chance analysis has begun. “Draft Scope”: EPA has released a draft scope document for community remark. “Ultimate Scope”: EPA has posted a ultimate scope doc (or issue formulation for the 1st 10).

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which are derived from structural information118 or the presence of structural alerts58 contain two resources of uncertainty which can compound the mistake of

Organizations working with the prioritized chemicals should proactively converse their disorders of use (COU) for the EPA. Producing information about prospective exemptions through risk evaluation, notifying the agency about ongoing reports, and conveying suitable information in the course of comment intervals is buy research chems us going to be critical.

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EPA may revise the designation of a Minimal-Precedence Compound to the Higher-Priority Material determined by information and facts accessible to the Administrator.  The process for revising such a designation entails restarting the prioritization approach, which include re-initiating, re-proposing and re-finalizing a designation, and would essentially deliver exactly the same options for community comment. 

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